Advise female patients of reproductive opportunity that utilization of OXYCONTIN for an extended stretch of time throughout pregnancy may end up in neonatal opioid withdrawal syndrome, which may be everyday living-threatening Otherwise regarded and taken care of [see WARNINGS AND Safety measures and Use In Particular Populations].

In case you are using a liquid type of this medication, use a medication measuring unit to meticulously measure the prescribed dose. Don't use a family spoon as you may well not get the right dose.

Oxycodone hydrochloride tablets are a right away-release oral formulation of oxycodone hydrochloride indicated for your administration of moderate to serious soreness wherever the use of an opioid analgesic is suitable.

A solid prescription discomfort medicine which contains an opioid (narcotic) that may be utilized to control severe and persistent ache, that needs an prolonged therapy time period with a day-to-day opioid discomfort medicine when other ache medicines do not treat your agony well sufficient or You can't tolerate them.

Don't flush medicines down the bathroom or pour them into a drain Until instructed to do so. Correctly discard this product when it is actually expired or now not desired. For more details, browse the Medication Tutorial, or talk to your pharmacist or regional waste disposal firm.

In a scientific trial supporting the event of oxycodone hydrochloride tablets, too handful of clients with diminished hepatic operate had read more been evaluated to check these potential variations.

Oxycodone is a complete opioid agonist and is comparatively selective for your mu receptor, although it can bind to other opioid receptors at better get more info doses. The principal therapeutic action of oxycodone is analgesia.

Usage of opioid analgesics for an prolonged time period during pregnancy for health-related or nonmedical uses can result in Bodily dependence within the neonate and neonatal opioid withdrawal syndrome Soon just after delivery.

The more info respiratory depressant outcomes of narcotics and their potential to elevate cerebrospinal fluid tension can be markedly exaggerated from the presence of head injuries, other intracranial lesions or perhaps a pre-present rise in intracranial stress.

If a CYP3A4 inhibitor is discontinued, take into account expanding the OXYCONTIN dosage until finally steady get more info drug consequences are attained. Assess for signs of opioid withdrawal.

Keep away from eating grapefruit or consuming grapefruit juice while working with this medication unless your medical doctor or pharmacist claims you might do this safely and securely. Grapefruit can raise the potential for side effects with this medicine. Request your doctor or pharmacist for more specifics.

Before taking oxycodone, tell your doctor or pharmacist If you're allergic to it; or to other opioid discomfort relievers (like oxymorphone); or When you have another allergic reactions.

Physical dependence results in withdrawal signs in sufferers who abruptly discontinue the drug or could be precipitated throughout the administration of drugs with opioid antagonist activity. If oxycodone hydrochloride tablets are abruptly discontinued in a bodily dependent individual, an abstinence syndrome could happen (see DRUG ABUSE AND DEPENDENCE).

If the decision is manufactured to prescribe a benzodiazepine or other CNS depressant oxycodone 10 mg virkningstid concomitantly with an opioid analgesic, prescribe the bottom efficient dosages and minimum amount durations of concomitant use. In individuals by now acquiring an opioid analgesic, prescribe a lower Preliminary dose of your benzodiazepine or other CNS depressant than indicated within the absence of an opioid, and titrate depending on scientific reaction.